Use of ovarian reserve markers to predict ovarian response in A.R.T: a prospective study

ABSTRACT

Our study is conducted in order to evaluate the correlation between ovarian reserve markers such as antral follicular count, baseline FSH, LH, E2 as well as Inhibin-B, with the prognosis of IVF/ICSI cycles, demonstrated by the number of eggs retrieved. Through a prospective comparative study, 50 patients undergoing IVF/ICSI cycles were recruited in the study. Ovarian reserve markers, as well as the number of eggs retrieved were evaluated for all cases, and correlations were evaluated. Demonstrated that all of the ovarian reserve markers showed significant correlations with the number of eggs retrieved, duration of stimulation, rate of cancelled cycles for non response. Yet the antral follicular count showed the strongest correlation, followed by the bseline Estradiol, and baseline FSH. Antral follicular count can be used with high accuracy to evaluate and predict response to controlled ovarian stimulation in IVF/ICSI cycles, with comparable accuracy to other classic ovarian reserve markers, such as baseline hormone values