JMJ-Jamahiriya Medical Journal. 2007; 7 (3): 192-195
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| ID: emr-83288
Biblioteca responsável:
EMRO
ABSTRACT
Latanoprost has proven to be an effective ocular hypotensive in healthy eyes and in eyes with elevated intraocular pressure. In this study the effect on intraocular pressure [IOP] and safety profile of topical applications of Latanoprost alone or combined with Betaxolol is investigated. A total of 25 eyes [25 patients] with open angle glaucoma were included in a 3 months prospective study. Mean age was 55.25 years [range 34-69]. They were allocated to a 4 weeks treatment with once daily administration of Latanoprost 0.005%, followed by 8 weeks' combination with Betoptic 0.5% topical drops twice daily therapy. The effect of Latanoprost alone reduced IOP from 26.48 [SD +/- 5.16] to 20.92 [SD +/- 3.8] mm Hg [p <0.005]. The addition of Betopic eye drops produced further reduction of IOP to 15.16 [SD +/- 2.81] mm Hg [p <0.005]. Latanoprost have a clinically significant IOP lowering effect. The effect of Xalatan on IOP is increased when combined with Betaxolol. No serious side effects were reported
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Assunto principal:
Betaxolol
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Glaucoma de Ângulo Aberto
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Estudos Prospectivos
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Resultado do Tratamento
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Pressão Intraocular
Limite:
Female
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Humans
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Male
Idioma:
En
Revista:
Jamahiriya Med. J.
Ano de publicação:
2007