Inverse association between plasma cholesterol and gallstone disease
Arch. med. res
; Arch. med. res;30(3): 190-7, mayo-jun. 1999. tab
Article
em En
| LILACS
| ID: lil-256647
Biblioteca responsável:
MX1.1
ABSTRACT
Background. The association between gallstone disease (gallstones or cholecystectomy) and plasma lipids was evaluated in 2,089 subject who attended a private health care facility in Mexico city from august 1991 to August 1992. Methods. All participants provided data on their sociodemographic status, non-insulin dependent diabetes mellitus diagnoses, alcohol consumption, and smoking habits; women also gave data regarding their obstetric-gynecologic histories. Ultrasounds of the liver and biliary tract were performed. Cholesterol levels, high-density lipoproteins cholesterol, and triglyceride plasma concentration were determined. Results. This study shows a strong inverse association between gallstone disease and plasma cholesterol concentration, with OR = 0.61 (95 percent CI = 0.42-0.89) in the category of 181-239 mg/dL, and OR = 0.49 (95 percent CI 0.32-0.77) in the group of 240 mg/dL or more, when compared to 180 mg/dL or less, after adjusting for the following risk factors; gender, age, and body mass index. Conclusions. These results suggest an increment in the catabolic pool of cholesterol, reflected in lower levels of plasm cholesterol in subjects with gallstone disease
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Índice:
LILACS
Assunto principal:
Colelitíase
/
Colesterol
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Arch. med. res
Assunto da revista:
MEDICINA
Ano de publicação:
1999
Tipo de documento:
Article