Antigen incorporation on Cryptosporidium parvum oocyst walls
Mem. Inst. Oswaldo Cruz
;
96(2): 233-5, Feb. 2001. ilus
Artigo
em Inglês
| LILACS
| ID: lil-281573
ABSTRACT
Cryptosporidium parvum oocysts are the infective stages responsible for transmission and survival of the organism in the environment. In the present work we show that the oocyst wall, far from being a static structure, is able to incorporate antigens by a mechanism involving vesicle fusion with the wall, and the incorporation of the antigen to the outer oocyst wall. Using immunoelectron microscopy we show that the antigen recognized by a monoclonal antibody used for diagnosis of cryptosporidiosis (Merifluor®, Meridian Diagnostic Inc.) could be found associated with vesicles in the space between the sporozoites and the oocysts wall, and incorporated to the outer oocyst wall by an unknown mechanism
Texto completo:
DisponíveL
Índice:
LILACS (Américas)
Assunto principal:
Oócitos
/
Cryptosporidium parvum
/
Antígenos de Protozoários
Tipo de estudo:
Estudo diagnóstico
Limite:
Animais
Idioma:
Inglês
Revista:
Mem. Inst. Oswaldo Cruz
Assunto da revista:
Medicina Tropical
/
Parasitologia
Ano de publicação:
2001
Tipo de documento:
Artigo
País de afiliação:
Espanha
Instituição/País de afiliação:
Universidad de Granada/ES
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