Uso de fibrinolíticos en el tromboembolismo pulmonar (TEP) ¿Qué? ¿Cuándo? ¿Cuánto? / Fibrinolytic treatment in pulmonary thromboembolism. What to use? When? How much?

ABSTRACT

Severe pulmonary ambolism with sustained hypontension (less than 90 mmHg systolic pressure) or with cardiogenic shock requires urgent treatment with fibrinolytic drugs. Otherwise there is still no consensus with the use of fibrinolytics in patients witch are compensated but with right ventricular disfunction and even Dr. Goldhaber now seems to be cautious because of the high risk of intracraneal bleeding. The suggested dose is for t-PA 100 mg. IV in 2 hours, UK 1 millon U IV in 10 minutes and then 2 millons in 2 hours, SK 1.5 millon U. IV in 2 hours.