Mitochondrial Ca2+ homeostasis in health and disease

Campanella, Michelangelo; Pinton, Paolo; Rizzuto, Rosario

Campanella, Michelangelo; Pinton, Paolo; Rizzuto, Rosario.

Afiliação

Campanella, Michelangelo; University of Ferrara. Dept. Experimental and Diagnostic Medicine and Interdisciplinary Center for the Study of Inflammation. IT
Pinton, Paolo; University of Ferrara. Dept. Experimental and Diagnostic Medicine and Interdisciplinary Center for the Study of Inflammation. IT
Rizzuto, Rosario; University of Ferrara. Dept. Experimental and Diagnostic Medicine and Interdisciplinary Center for the Study of Inflammation. IT

Biol. Res ; 37(4): 653-660, 2004. ilus

Article em En | LILACS | ID: lil-437522

Biblioteca responsável: CL1.1

ABSTRACT

ABSTRACT

Although it has long been known that mitochondria possess a complex molecular repertoire for accumulating and releasing Ca2+, only in recent years has a large body of data demonstrated that these organelles promptly respond to Ca2+-mediated cell stimulations. In this contribution, we will review the principles of mitochondrial Ca2+ homeostasis and its signaling role in different physiological and pathological conditions.

Assuntos

Humanos; Apoptose/fisiologia; Cálcio/fisiologia; Cálcio/metabolismo; Canais de Cálcio/fisiologia; Canais de Cálcio/metabolismo; Homeostase/fisiologia; Sinalização do Cálcio/fisiologia; Transporte Biológico/fisiologia

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Texto completo: 1 Índice: LILACS Assunto principal: Canais de Cálcio / Cálcio / Apoptose / Homeostase Limite: Humans Idioma: En Revista: Biol. Res Assunto da revista: BIOLOGIA Ano de publicação: 2004 Tipo de documento: Article

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