Cloning and analysis of IFRG (interferon responsive gene) in rabbit oocytes and preimplantation embryos
Biocell
; 31(2): 199-203, ago. 2007. ilus
Article
em En
| LILACS
| ID: lil-491562
Biblioteca responsável:
AR40.1
ABSTRACT
Although there is more evidence that shows that IFNs (interferons) plays a very important role in the early development of the embryo, the mechanism of IFNs is still unclear. Our study showed that IFRG is expressed from oocytes- through to the preimplantation embryo in rabbits. This finding provides some clues for better understanding the role of IFNs in the development of the embryo. The full length of rabbit IFRG cDNA (Accession No. AJ584672), with a 2794bp encoding 131 amino acid sequence, was cloned IFRG expression can be detected in 8 different tissues ovary, heart, lung, liver, kidney, spleen, cerebra, and the 18-day whole-body embryo. Whole-mount in situ hybridization showed that IFRG was highly expressed in the inner-cell mass of rabbit blastula. IFRG may play an important role in embryo development and tissue differentiation.
Texto completo:
1
Índice:
LILACS
Assunto principal:
Oócitos
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Blastocisto
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RNA Mensageiro
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Interferons
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DNA Complementar
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Regulação da Expressão Gênica no Desenvolvimento
Limite:
Animals
Idioma:
En
Revista:
Biocell
Assunto da revista:
Clulas
Ano de publicação:
2007
Tipo de documento:
Article