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Pubarquia precoz: Experiencia en 173 casos / Precocious pubarche: Experience in 173 cases
Eyzaguirre, Francisca C; Bancalari, Rodrigo; Youlton, Ronald; Román, Rossana; Silva, Ricardo; García, Hernán; Mericq, Verónica.
Afiliação
  • Eyzaguirre, Francisca C; Universidad de Chile. Facultad de Medicina. Instituto de Investigaciones Materno Infantil.
  • Bancalari, Rodrigo; Universidad de Los Andes. Facultad de Medicina. Departamento de Pediatría. CL
  • Youlton, Ronald; Clínica las Condes. Unidad de Endocrinología. Departamento de Pediatría. CL
  • Román, Rossana; Universidad de Chile. Facultad de Medicina. Instituto de Investigaciones Materno Infantil.
  • Silva, Ricardo; Clínica Santa María. Unidad de Endocrinología. Departamento de Pediatría. CL
  • García, Hernán; Clínica Santa María. Unidad de Endocrinología. Departamento de Pediatría. CL
  • Mericq, Verónica; Universidad de Chile. Facultad de Medicina. Instituto de Investigaciones Materno Infantil.
Rev. méd. Chile ; 137(1): 31-38, ene. 2009. tab
Article em Es | LILACS | ID: lil-511841
Biblioteca responsável: BR1.1
ABSTRACT

Background:

Precocious pubarche (PP), defined as the development of sexual pubic hair before 8 years of age in females and before 9 years in males, is usually a benign condition but it can also be the first sign of an underlying disease.

Aim:

To analyze the etiology andperform a short term follow up in a cohort of patients with PP. Material and

methods:

A group of 173 patients (158 females) consulted for PP with a mean age of 7.4±0.1 years. These patients were followed between 15 to 60 months. Anthropometric measurements, bone age, serum levels of total testosterone, 17 OH progesterone (17 OHP) and dehydroepiandrosterone sulphate (DHEAS) were evaluated.

Results:

Mean birth weight and length was 3024.1±50.5 g and 48.5±0.3 cm,respectively. Ten percent of children were small for gestational age at birth. Bone age was accelerated by 1.1±0.01 years. One hundred and twelve patients were classified as having idiopathicPP (64.7%; 105 females), 29 as central precocious puberty (16.8%; only females), 16 as exaggerated adrenarche (EA 9.2%; 13 females) and 16 as non classical adrenal hyperplasia (9.2%; 11 females).

Conclusions:

PP represents a common and usually benign sign. However, 26% of cases had apathologic underlying condition. Therefore, all children with PP should be evaluated by a pediatric endocrinologist. Low birth weight was not frequent in this cohort and these patients did not show EA
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Texto completo: 1 Índice: LILACS Assunto principal: Puberdade Precoce / Peso ao Nascer Tipo de estudo: Diagnostic_studies Limite: Child / Female / Humans / Male / Newborn País/Região como assunto: America do sul / Chile Idioma: Es Revista: Rev. méd. Chile Assunto da revista: MEDICINA Ano de publicação: 2009 Tipo de documento: Article
Texto completo: 1 Índice: LILACS Assunto principal: Puberdade Precoce / Peso ao Nascer Tipo de estudo: Diagnostic_studies Limite: Child / Female / Humans / Male / Newborn País/Região como assunto: America do sul / Chile Idioma: Es Revista: Rev. méd. Chile Assunto da revista: MEDICINA Ano de publicação: 2009 Tipo de documento: Article