A description of genes of Corynebacterium pseudotuberculosis useful in diagnostics and vaccine applications
Genet. mol. res. (Online)
; 7(1): 252-260, Jan. 2008.
Article
em En
| LILACS
| ID: lil-553792
Biblioteca responsável:
BR26.1
ABSTRACT
Corynebacterium pseudotuberculosis, a Gram-positive intracellular pathogen, is the etiological agent of caseous lymphadenitis or CLA. This bacterium infects goats and sheep and causes great economic losses worldwide annually, mainly for goat producers. Despite its importance, CLA is still poorly characterized. However, with advances in the genomic field, many C. pseudotuberculosis genes have already been characterized, mainly those related to virulence such as phospholipase D. Here, we examined the use of the several available genes of C. pseudotuberculosis and reviewed their applications in vaccine construction, more efficient diagnostics for CLA, and control of this disease, among other applications.
Palavras-chave
Texto completo:
1
Índice:
LILACS
Assunto principal:
Corynebacterium pseudotuberculosis
/
Infecções por Corynebacterium
Tipo de estudo:
Diagnostic_studies
Limite:
Animals
Idioma:
En
Revista:
Genet. mol. res. (Online)
Assunto da revista:
BIOLOGIA MOLECULAR
/
GENETICA
Ano de publicação:
2008
Tipo de documento:
Article
/
Project document