Survival and quality of life of patients with oral and oropharyngeal cancer at 1-year follow-up of tumor resection
J. appl. oral sci
; J. appl. oral sci;18(3): 279-284, May-June 2010. ilus, tab
Article
em En
| LILACS
| ID: lil-557094
Biblioteca responsável:
BR1.1
ABSTRACT
OBJECTIVE:
This study aimed to assess the survival and life quality evolution of patients subjected to surgical excision of oral and oropharyngeal squamous cell carcinoma. MATERIAL ANDMETHODS:
Forty-seven patients treated at a Brazilian healthcare unit specialized in head and neck surgery between 2006 and 2007 were enrolled in the study. The gathering of data comprised reviewing hospital files and applying the University of Washington Quality of Life (UW-QOL) questionnaire previously and 1 year after the surgery. Comparative analysis used Poisson regression to assess factors associated with survival and a paired t-test to compare preoperative and 1-year postoperative QOL ratings.RESULTS:
1 year after surgery, 7 patients were not found (dropout of the cohort); 15 had died and 25 fulfilled the UW-QOL again. The risk of death was associated with having regional metastasis previously to surgery (relative risk=2.18; 95 percent confidence interval=1.09-5.17) and tumor size T3 or T4 (RR=2.30; 95 percentCI=1.05-5.04). Survivors presented significantly (p<0.05) poorer overall and domain-specific ratings of quality of life. Chewing presented the largest reduction from 74.0 before surgery to 34.0 one year later. Anxiety was the only domain whose average rating increased (from 36.0 to 70.7).CONCLUSIONS:
The prospective assessment of survival and quality of life may contribute to anticipate interventions aimed at reducing the incidence of functional limitations in patients with oral and oropharyngeal cancer.Palavras-chave
Texto completo:
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Índice:
LILACS
Assunto principal:
Qualidade de Vida
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Neoplasias Bucais
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Carcinoma de Células Escamosas
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Neoplasias Orofaríngeas
Tipo de estudo:
Etiology_studies
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Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Female
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Humans
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Male
Idioma:
En
Revista:
J. appl. oral sci
Assunto da revista:
ODONTOLOGIA
Ano de publicação:
2010
Tipo de documento:
Article
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Project document