Detección de inflamación en placa aterosclerosa: rol de la tomografía por emisión de positrones y de la proteína C reactiva / Detection of inflammation in an atherosclerose plaque: the role of the positron emission tomography and C reactive protein
Arch. cardiol. Méx
; 77(4): 288-294, oct.-dic. 2007. tab, ilus
Article
em Es
| LILACS
| ID: lil-567021
Biblioteca responsável:
BR1.1
ABSTRACT
OBJECTIVES:
To demonstrate that inflammatory atheromatose carotid plaques can be visualized with positron emission tomography with 18F-fluorodeoxyglucose (18FDG PET) in symptomatic patients, in order to correlate them with systemic inflammatory markers, such as CRP.METHOD:
Fifteen patients with cerebral ischemia due to atherosclerotic carotid disease were studied. 18FDG uptake with PET was considered and blood samples were taken for determining high sensibility C reactive protein (HsCRP).RESULTS:
The mean age of the patients was 66 years; 11 of them were males (73%) and 4 were females (27%). 18FDG PET was positive in 12 patients (80%), while 100% of the studied population had low risk HsCRP with normal white cell count.CONCLUSIONS:
18FDG PET proves active inflammation in carotid atheromatose plaques. There was no significant correlation between the presence of ahteromatose carotid plaques, HsCRP serum levels, and 18FDG PET study.
Texto completo:
1
Índice:
LILACS
Assunto principal:
Proteína C-Reativa
/
Doenças das Artérias Carótidas
/
Tomografia por Emissão de Pósitrons
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Aged
/
Aged80
/
Female
/
Humans
/
Male
Idioma:
Es
Revista:
Arch. cardiol. Méx
Assunto da revista:
CARDIOLOGIA
Ano de publicação:
2007
Tipo de documento:
Article