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Circadian stage-dependent effect of acth and melatonin on protein synthesis by rat adrenal cells
Braz. j. med. biol. res ; 21(4): 759-62, 1988. tab
Article em En | LILACS | ID: lil-60777
Biblioteca responsável: BR26.1
ABSTRACT
The objective of the study was to determine the circadian effects of melatonin and two different ACTH preparations a synthetic heptadecapeptide with adrenocorticotrophic action (synchrodyn 1-17, HOE 433) and a natural ACTH (Acthar, Armour). Both ACTH preparations acted in a circadian stage-dependent fashion affecting the MESOR and the amplitude of total protein synthesis of rat adrenal cells. The results also indicated interaction of melatonin with the rhythmic action of ACTH. We conclude that circadian adrenocortical organization also modulates protein

synthesis:

Assuntos
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Índice: LILACS Assunto principal: Ritmo Circadiano / Glândulas Suprarrenais / Hormônio Adrenocorticotrópico / Melatonina Limite: Animals Idioma: En Revista: Braz. j. med. biol. res Assunto da revista: BIOLOGIA / MEDICINA Ano de publicação: 1988 Tipo de documento: Article / Congress and conference / Project document
Buscar no Google
Índice: LILACS Assunto principal: Ritmo Circadiano / Glândulas Suprarrenais / Hormônio Adrenocorticotrópico / Melatonina Limite: Animals Idioma: En Revista: Braz. j. med. biol. res Assunto da revista: BIOLOGIA / MEDICINA Ano de publicação: 1988 Tipo de documento: Article / Congress and conference / Project document