Protective effects of Tualang honey on bone structure in experimental postmenopausal rats
Clinics
; 67(7): 779-784, July 2012. ilus, tab
Article
em En
| LILACS
| ID: lil-645451
Biblioteca responsável:
BR1.1
ABSTRACT
OBJECTIVE:
The objective of this study was to evaluate the effects of Tualang honey on trabecular structure and compare these effects with those of calcium supplementation in ovariectomized rats.METHODS:
Forty female, Sprague-Dawley rats were randomly divided into five groups (n =8) four controls and one test arm. The control arm comprised a baseline control, sham-operated control, ovariectomized control, and ovariectomized calcium-treated rats (receiving 1% calcium in drinking water ad libitum). The test arm was composed of ovariectomized, Tualang honey-treated rats (received 0.2 g/kg body weight of Tualang honey). Both the sham-operated control and ovariectomized control groups received vehicle treatment (deionized water), and the baseline control group was sacrificed without treatment.RESULTS:
All rats were orally gavaged daily for six weeks after day one post-surgery. The bone structural analysis of rats in the test arm group showed a significant increase in the bone volume per tissue volume (BV/TV), trabecular thickness (Tb.Th) and trabecular number (Tb.N) and a significant decrease in inter-trabecular space (Tb.Sp) compared with the ovariectomized control group. The trabecular thickness (Tb.Th) in the test arm group was significantly higher compared with the ovariectomized-calcium treated group, and the inter-trabecular space (Tb.Sp) in the test arm group was significantly narrower compared with the ovariectomized-calcium treated group.CONCLUSION:
In conclusion, ovariectomized rats that received Tualang honey showed more improvements in trabecular bone structure than the rats that received calcium.Palavras-chave
Texto completo:
1
Índice:
LILACS
Assunto principal:
Cálcio da Dieta
/
Densidade Óssea
/
Suplementos Nutricionais
/
Apiterapia
/
Mel
Limite:
Animals
Idioma:
En
Revista:
Clinics
Assunto da revista:
MEDICINA
Ano de publicação:
2012
Tipo de documento:
Article
/
Project document