Your browser doesn't support javascript.
loading
Long-term cytotoxic effects of contemporary root canal sealers
Silva, Emmanuel João Nogueira Leal da; Santos, Carolina Carvalho; Zaia, Alexandre Augusto.
Afiliação
  • Silva, Emmanuel João Nogueira Leal da; University of Campinas. Piracicaba Dental School. Piracicaba. BR
  • Santos, Carolina Carvalho; University of Campinas. Piracicaba Dental School. Piracicaba. BR
  • Zaia, Alexandre Augusto; University of Campinas. Piracicaba Dental School. Piracicaba. Endodontics Department. BR
J. appl. oral sci ; J. appl. oral sci;21(1): 43-47, 2013. tab, graf
Article em En | LILACS, BBO | ID: lil-684994
Biblioteca responsável: BR28.1
ABSTRACT

Objectives:

The aim of the present study was to investigate the effects of root canal sealers on the cytotoxicity of 3T3 fibroblasts during a period of 5 weeks. Material and

Methods:

Fibroblasts (3T3, 1×105 cells per well) were incubated with elutes of fresh specimens from eight root canal sealers (AH Plus, Epiphany, Endomethasone N, EndoREZ, MTA Fillapex, Pulp Canal Sealer EWT, RoekoSeal and Sealapex) and with elutes of the same specimens for 5 succeeding weeks after immersing in simulated body fluid. The cytotoxicity of all root canal sealers was determined using the MTT assay. Data were analyzed using ANOVA and Tukey's test.

Results:

RoekoSeal was the only sealer that did not show any cytotoxic effects (p<0.05). All the other tested sealers exhibited severe toxicity initially (week 0). MTA Fillapex remained moderately cytotoxic after the end of experimental period. Toxicity of the other tested sealers decreased gradually over time. The evaluated root canal sealers presented varying degrees of cytotoxicity, mainly in fresh mode.

Conclusions:

RoekoSeal had no cytotoxic effect both freshly mixed and in the other tested time points. MTA Fillapex was associated with significantly less cell viability when compared to the other tested root canal sealers.
Assuntos
Palavras-chave

Texto completo: 1 Índice: LILACS Assunto principal: Materiais Restauradores do Canal Radicular Limite: Animals Idioma: En Revista: J. appl. oral sci Assunto da revista: ODONTOLOGIA Ano de publicação: 2013 Tipo de documento: Article

Texto completo: 1 Índice: LILACS Assunto principal: Materiais Restauradores do Canal Radicular Limite: Animals Idioma: En Revista: J. appl. oral sci Assunto da revista: ODONTOLOGIA Ano de publicação: 2013 Tipo de documento: Article