Prevention of peritoneal adhesion using a bacterial cellulose hydrogel, in experimental study
Acta cir. bras
; 30(3): 194-198, 03/2015. tab
Article
em En
| LILACS
| ID: lil-741041
Biblioteca responsável:
BR1.1
ABSTRACT
PURPOSE:
To analyze the effectiveness of bacterial cellulose hydrogel as a barrier in preventing postoperative peritoneal adhesion in rat model.METHODS:
Experimental study with 45 Wistar rats (Rattus norvegicus) that were divided into three groups for the following treatments A. Saline, B. Oxidized Regenerated Cellulose (ORC) barrier, and C Bacterial Cellulose Hydrogel (BCH) barrier. After 45 days of the surgery the adhesions were classified and graded according to the qualitative score. The histological parameters were evaluated using a modified semi-quantitative scale to rate the extent of fibrosis, inflammatory reaction and vascular proliferation.RESULTS:
Compared with the saline group (A), the treatments with ORC barrier (B) and BHC barrier (C) resulted in a smaller number of adhesions (p=0.019 and p=0.003 on Fisher's exact test, respectively). Data from inflammation and neovascularization showed no statistically significant difference between the groups BHC and ORC (p=0.426 and 0.446 on chi-square test, respectively).CONCLUSION:
Bacterial cellulose hydrogel is effective as a bio-re-absorbable barrier for preventing postoperative peritoneal adhesions. .Palavras-chave
Texto completo:
1
Índice:
LILACS
Assunto principal:
Próstata
/
Neoplasias da Próstata
/
Imageamento por Ressonância Magnética
/
Gadolínio DTPA
/
Pontos de Referência Anatômicos
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
/
Qualitative_research
Limite:
Adult
/
Aged
/
Humans
/
Male
Idioma:
En
Revista:
Acta cir. bras
Assunto da revista:
CIRURGIA GERAL
/
Procedimentos Cir£rgicos Operat¢rios
Ano de publicação:
2015
Tipo de documento:
Article