Changes in choline acetyltransferase activity of rat tissues during Chagas' disease
Braz. j. med. biol. res
; 20(6): 697-702, 1987. tab
Article
em En
| LILACS
| ID: lil-77418
Biblioteca responsável:
BR26.1
RESUMO
1. The activity of choline acetyltransferase (CAT) measured by a radilabeling method was significantly reduced in the heart, submandibular gland and esophagus of rats 20 days after inoculation with Trypanosoma cruzi (Y strain). 2. Normal enzyme activity was recovered in all these organs 100 days after inoculation. 3. In the transcerse colon, no change, 30% reduction and normal activity were found at days 20, 100 and 430 of infection, respectively. 4. The data indicate recovery of parasympathetic function in experimental Chagas' disease. Axonal regrowth and sprouting are discussed as possible candidates for the recovery mechanisms
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Índice:
LILACS
Assunto principal:
Sistema Nervoso Parassimpático
/
Glândula Submandibular
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Colina O-Acetiltransferase
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Doença de Chagas
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Esôfago
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Miocárdio
Limite:
Animals
Idioma:
En
Revista:
Braz. j. med. biol. res
Assunto da revista:
BIOLOGIA
/
MEDICINA
Ano de publicação:
1987
Tipo de documento:
Article
/
Project document