Cases of human immunodeficiency virus infection and tuberculosis--early experiences of different aspects.
J Indian Med Assoc
; 2003 May; 101(5): 291-2, 294, 296 passim
Article
em En
| IMSEAR
| ID: sea-105487
ABSTRACT
An outpatients department based survey conducted in Calcutta amongst 1349 established cases of tuberculosis (TB) revealed 0.67% human immunodeficiency virus (HIV) infected cases. Those affected by HIV and TB did not show any deviation from epidemiological pattern of HIV infection in India. All contracted HIV infection by heterosexual route, mostly from Bombay (47.8%) followed by West Bengal (30.4%). In follow-up study of a cohort of 36 HIV seropositives over 3 years, 10(27.7%) developed TB. Of the 23 HIV infected cases with TB, lesions were mostly pulmonary (n = 18, 78.3%) followed by pleural effusion (n = 3;13%). Low incidence of Mycobacterium avium (intracelluarae) complex and tuberculous lymphadenopathy one case each and 52.2% positivity with 14.5 mm mean induration diameter in intradermal test with one TU PPD-RT23 are deviations from previous reports. Low incidence of cough (43.5%), marked weight loss (100%) and fever (100%) were the cardinal clinical features. TB infection on pattern suggestive of reactivation of dormant pulmonary lesions lower rate (11%) of treatment failure and infection caused by organisms other than Mycobacterium tuberculosis were other findings of the study. Importance of serosurveillance to unearth more TB cases amongst HIV infected cases for early treatment and isoniazid prophylaxis is stressed upon.
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IMSEAR
Assunto principal:
Tuberculose Pleural
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Tuberculose Pulmonar
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Feminino
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Humanos
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Masculino
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Estudos de Coortes
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Seguimentos
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Soropositividade para HIV
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Adulto
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Índia
Tipo de estudo:
Etiology_studies
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Incidence_studies
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Observational_studies
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Prognostic_studies
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Risk_factors_studies
País/Região como assunto:
Asia
Idioma:
En
Revista:
J Indian Med Assoc
Ano de publicação:
2003
Tipo de documento:
Article