Intestinal metaplasia--its association with gastric cancer.
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| ID: sea-124945
ABSTRACT
Endoscopic gastric biopsies from 230 patients and post gastrectomy specimens of 18 patients were evaluated for the presence of intestinal metaplasia (IM) and its association with the gastric lesions. There were a total of 78 malignant and 170 benign lesions. IM was present in 53% of patients with gastric carcinoma (GC) and in 10.6% with benign lesions of the stomach. The IM in association with GC was of type 1 (Small Intestinal) in 58.8%; type II (mixed gastric and small intestinal) in 11.8% and type III (Colonic) in 29.4%. In patients with benign lesions the IM was predominantly of type I (94.5%) except in 1 patient who had type III metaplasia. Our findings indicate that type III IM was significantly more frequent in patient with GC than with benign lesions (29.4% Vs 5.5%; p < .005). Therefore we conclude that patients with type III IM should be kept on surveillance for GC.
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Assunto principal:
Prognóstico
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Neoplasias Gástricas
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Biópsia
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Humanos
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Endoscopia
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Gastrectomia
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Enteropatias
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Metaplasia
Tipo de estudo:
Prognostic_studies
Idioma:
En
Ano de publicação:
1995
Tipo de documento:
Article