Principles of sample size calculation.
Indian J Ophthalmol
; 2010 Nov; 58(6): 517-518
Article
em En
| IMSEAR
| ID: sea-136116
ABSTRACT
In most areas in life, it is difficult to work with populations and hence researchers work with samples. The calculation of the sample size needed depends on the data type and distribution. Elements include consideration of the alpha error, beta error, clinically meaningful difference, and the variability or standard deviation. The final number arrived at should be increased to include a safety margin and the dropout rate. Over and above this, sample size calculations must take into account all available data, funding, support facilities, and ethics of subjecting patients to research.
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IMSEAR
Assunto principal:
Humanos
/
Ensaios Clínicos como Assunto
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Interpretação Estatística de Dados
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Tamanho da Amostra
Idioma:
En
Revista:
Indian J Ophthalmol
Ano de publicação:
2010
Tipo de documento:
Article