Chromosomal abnormalities associated with mental retardation in female subjects.
Indian J Hum Genet
; 2009 Jan; 15(1): 28-31
Article
em En
| IMSEAR
| ID: sea-138867
ABSTRACT
Chromosomal abnormalities are thought to be the most common cause of mental retardation (MR). However, apart from a few selected types with typical aneuploidy, like Downs syndrome, Klinefelter syndrome, Turner syndrome, etc., the frequency of detectable chromosomal abnormalities in association with idiopathic MR is very low. In this study, we have investigated chromosomal abnormalities in female MR subjects (n = 150) by high-resolution GTG banding. Of them, 30 cases were diagnosed as Downs syndrome. Among the remaining (n = 120), chromosomal abnormalities/marked polymorphisms were detectable in only three MR cases (0.025).
Palavras-chave
Texto completo:
1
Índice:
IMSEAR
Assunto principal:
Polimorfismo Genético
/
Feminino
/
Humanos
/
Aberrações Cromossômicas
/
Bandeamento Cromossômico
/
Síndrome de Down
/
Cariótipo
/
Deficiência Intelectual
Idioma:
En
Revista:
Indian J Hum Genet
Ano de publicação:
2009
Tipo de documento:
Article