Comet assay in neonatal sepsis.
Indian J Pediatr
; 2010 Aug; 77(8): 875-877
Article
em En
| IMSEAR
| ID: sea-142653
ABSTRACT
Objective. To determine whether the DNA damage detected using the Comet assay helps in the diagnosis of neonatal sepsis Methods. Sepsis was diagnosed, based on clinical findings, laboratory findings and positive culture results, in 24 of the 48 newborns who participated in the study. Hematological parameters, baseline demographic data and genotoxic evaluation were investigated. Results. There were no significant differences in hematological, demographic and genotoxic data between cases and controls. Conclusions. The Comet assay proved to be ineffective in the diagnosis of neonatal sepsis.
Palavras-chave
Texto completo:
1
Índice:
IMSEAR
Assunto principal:
Dano ao DNA
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Feminino
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Humanos
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Masculino
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Recém-Nascido
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Curva ROC
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Sepse
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Ensaio Cometa
Tipo de estudo:
Prognostic_studies
Idioma:
En
Revista:
Indian J Pediatr
Ano de publicação:
2010
Tipo de documento:
Article