Complement-dependent lymphocytotoxicity crossmatch in deceased donor renal transplant: A single institutional experience.
Indian J Med Microbiol
; 2011 Oct-Dec; 29(4): 414-417
Article
em En
| IMSEAR
| ID: sea-143867
ABSTRACT
Complement-dependent lymphocytotoxicity crossmatches (n=217) between 47 deceased donors and 150 potential renal recipients were retrospectively studied. A negative cross match was reported in 48 (22.1%), doubtful positive in 126 (58.1%), weakly positive in 32 (14.7%) and positive in 11 (5.1%). No autoantibodies were detected. Renal transplantation was performed in 35.5% of the potential recipients. There was no incidence of hyperacute rejection. The graft survival rate was 88% at 15 months of follow up. The study concludes that a negative pretransplant lympocytotoxicity crossmatch using the basic National Institute of Health technique eliminates hyperacute rejection, but carries drawbacks, which require modification and supplementation with more sensitive and specific assays.
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IMSEAR
Assunto principal:
Idoso
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Feminino
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Humanos
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Masculino
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Proteínas do Sistema Complemento
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Testes Imunológicos de Citotoxicidade
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Teste de Histocompatibilidade
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Criança
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Pré-Escolar
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Estudos Retrospectivos
Tipo de estudo:
Observational_studies
Idioma:
En
Revista:
Indian J Med Microbiol
Assunto da revista:
Microbiology
Ano de publicação:
2011
Tipo de documento:
Article