Antioxidant potential and oxidative DNA damage preventive activity of unexplored endemic species of Curcuma.
Indian J Exp Biol
; 2014 Feb; 52(2): 133-138
Article
em En
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| ID: sea-150341
ABSTRACT
Free radical scavenging activity, ferrous ion chelating capacity, reducing power and genoprotective effect of the aqueous leaf extracts of four unexplored endemic Curcuma spp. (C. vamana, C. neilgherrensis, C. mutabilis, C. haritha) were found to be dose-dependent and were highest in C. vamana. DNA protection property of the extracts was evaluated against H2O2/UV-induced oxidative damage. DNA-methyl green displacement assay showed that these extracts were free of DNA intercalating compounds. Further, hemolysis assay also showed that the extracts were non-toxic to human erythrocytes. The results highlight C. vamana as a promising source for herbal preparations possessing high antioxidant potential and genoprotective activity.
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IMSEAR
Assunto principal:
Dano ao DNA
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Humanos
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Extratos Vegetais
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Quelantes de Ferro
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Sequestradores de Radicais Livres
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Physarum polycephalum
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Folhas de Planta
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Estresse Oxidativo
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DNA de Plantas
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Curcuma
Idioma:
En
Revista:
Indian J Exp Biol
Ano de publicação:
2014
Tipo de documento:
Article