‘Childhood systemic mastocytosis associated with t (8; 21) (q22; q22) acute myeloid leukemia’.
Indian J Pathol Microbiol
; 2016 July-Sept 59(3): 407-409
Article
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| ID: sea-179608
ABSTRACT
Systemic mastocytosis (SM) with associated clonal nonmast cell lineage disease is seen in up to 20% cases of SM. SM is uncommon in the pediatric population. T (8; 21) (q22; q22) is a good prognostic factor in acute myeloid leukemia (AML). However, the presence of SM confers poor prognosis in t (8; 21) (q22; q22) associated AML. We report the case of a child with t (8; 21) (q22; q22) associated AML with SM and her minimal residual disease status over the course of her treatment. In our case, the abnormal mast cells, showing co‑expression of CD25 and CD2, persisted even after the marrow showed no evidence of residual AML.
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IMSEAR
Tipo de estudo:
Prognostic_studies
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En
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Indian J Pathol Microbiol
Ano de publicação:
2016
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Article