Mortality & clinical characteristics of hospitalized adult patients with HIV in Pune, India.
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| ID: sea-19173
ABSTRACT
BACKGROUND & OBJECTIVE:
In India, data regarding mortality and clinical characteristics of hospitalized HIV-infected patients are sparse, which may limit the effectiveness of new hospital-based HIV programmes providing antiretroviral therapy (ART). The objective of our study was to determine mortality and clinical characteristics of hospitalized HIV-infected individuals in a high HIV prevalence region of India.METHODS:
A retrospective chart review was done of known HIV-infected adults admitted to the Medical Service of a large, public hospital in Pune, India, from January 2002 to November 2003.RESULTS:
A total of 655 HIV-infected patients were identified; 489 (74.7%) were male and 4 (0.6%) were on ART. The most common illnesses reported were tuberculosis (55.8%), diarrhoea (4.2%), and alcoholic liver disease (3.7%) . The inpatient mortality was 172 (26.3%). The most common causes of death of the 172 people were tuberculosis (52.9%) and cryptococcal meningitis (7.6%). In multivariate analysis, factors associated with increased mortality were male sex (adjusted odds ratio (AOR) 1.92, 95% CI 1.08-3.41), haemoglobin level < 7 g/dl (AOR 2.75, 95% CI1.23-6.14), length of stay < 2 days (OR 5.78, 95%, CI 1.82-18.4), and cryptococcal meningitis (OR 4.44, 95% CI1.19-16.6). INTERPRETATION &CONCLUSION:
In the era prior to widespread ART, a high inpatient mortality of 26 per cent was found among hospitalized HIV-infected individuals. Thus, while hospitalization is an important access and referral point for HIV care and treatment, earlier identification of HIV-infected persons must occur to ensure they will optimally benefit from the government's ART programme.
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IMSEAR
Assunto principal:
Tuberculose
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Idoso de 80 Anos ou mais
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Idoso
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Feminino
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Humanos
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Masculino
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Infecções por HIV
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Estudos Retrospectivos
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Meningite Criptocócica
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Adulto
Tipo de estudo:
Observational_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Aged80
País/Região como assunto:
Asia
Idioma:
En
Ano de publicação:
2007
Tipo de documento:
Article