Antidepressant and Antiamnesic Potential of Foeniculum vulgare
Article
| IMSEAR
| ID: sea-210200
ABSTRACT
Aim:
To evaluate the antiamnesic and antidepressant effect of Foeniculumvulgarewhole crushed seeds.StudyDesign:
Laboratory based randomized control study. Place and Duration of StudyDepartment of Pharmacology, University of Karachi between January 2018 to August 2018.Methodology:
Thirty swiss albino mice and wistar rats were divided equally in three groups. Control group was fed on standard rodent diet, group 2 was fed on 2% Foeniculumvulgarediet and group 3 was given 4% Foeniculumvulgarediet. Antidepressant activity was assessed using forced swimming test. Memory enhancement effect was evaluated by stationary rod test, passive avoidance test and water maze test.Results:
Increased durationof struggling time was noted in both group 2 and group 3 as compared to control in forced swimming test. Decrease in time to reach platform in both water maze and stationary rod test was recorded in both the study group (group 2 & 3). Increase in stepthroughlatency was also seen in group 2 and group 3 as compared to control group.Conclusion:
The results showed the memory enhancing and antidepressant actions of Foeniculum
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Índice:
IMSEAR
Tipo de estudo:
Clinical_trials
Ano de publicação:
2020
Tipo de documento:
Article