Guillain-Barre syndrome in Thai children: retrospective analysis of the clinical and outcome prior to intravenous immune globulin era.

ABSTRACT

The authors retrospectively reviewed Guillain-Barre syndrome (GBS) in 48 Thai children over a period of 20 years from 1970 to 1989. The clinical presentations of this syndrome were compared to those reported in previous studies of children in Western and Asian countries. Antecedent infection, including respiratory tract infection and nonspecific viral infection, in this group of patients is similar to previous studies in children. Cranial nerve involvement found in this study (45.8%) was higher than that in other studies. The outcome of GBS in Thai children in this study was not different from other reports even without IVIG administration. The authors emphasize that respiratory and supportive care are important in managing patients suffering from this syndrome.