Effect of arsenic on cell growth of the cellular slime mould, Dictyostelium discoideum.
Indian J Exp Biol
; 2003 Nov; 41(11): 1300-5
Article
em En
| IMSEAR
| ID: sea-58710
ABSTRACT
The growing D. discoideum cells were killed in a dose-dependent manner when exposed to 100 and 140 ppm of arsenic (As2O3) at mid-log phase for 20 min. Reduced plaque sizes and changed cell and colony morphologies were observed in the treated cells. Endocytotic functions (both phagocytosis and pinocytosis) were also inhibited in the treated cells. Arsenic treated cell showed a lower DNA and protein synthetic activities. These findings are discussed in relation to known mechanism of action of the heavy metal on growth-related cellular functions.
Texto completo:
1
Índice:
IMSEAR
Assunto principal:
Fagocitose
/
Pinocitose
/
Arsênio
/
DNA
/
Proteínas
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Divisão Celular
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Dictyostelium
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Endocitose
/
Animais
Idioma:
En
Revista:
Indian J Exp Biol
Ano de publicação:
2003
Tipo de documento:
Article