Beneficial effects of Zingiber officinale Roscoe on fructose induced hyperlipidemia and hyperinsulinemia in rats.
Indian J Exp Biol
; 2005 Dec; 43(12): 1161-4
Article
em En
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| ID: sea-59814
ABSTRACT
Fructose supplementation produced cardinal features of Syndrome-X including significant elevations in seum cholesterol, triglyceride, glucose and insulin and also in body weight. While treatment with methanolic extract of dried rhizomes of Zingiber officinale produced a significant reduction in fructose induced elevation in lipid levels, bodyweight, hyperglycemia and hyperinsulinemia, treatment with ethyl acetate extract of Z officinale did not poduce any significant change in either of the last two parameters. However, it produced a significant reduction in elevated lipid levels and body weight The concentration of 6-gingerol was found to be higher in methanolic extract and less in ethyl acetate extract. The results suggest that the methanolic extract of Z officinale produces better effects as compared to ethyl acetate extract in fructose induced hyperlipidemia associated with insulin resistance. The extent of activity appears to be dependent on the concentration of 6-gingerol present in the extracts.
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IMSEAR
Assunto principal:
Ratos
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Peso Corporal
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Extratos Vegetais
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Catecóis
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Zingiber officinale
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Rizoma
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Síndrome Metabólica
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Diabetes Mellitus Experimental
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Álcoois Graxos
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Frutose
Idioma:
En
Revista:
Indian J Exp Biol
Ano de publicação:
2005
Tipo de documento:
Article