Acetylhomocysteine thiolactone protection against phosphamidon-induced alteration of regional superoxide dismutase activity in the central nervous system and its correlation with altered lipid peroxidation.
Indian J Exp Biol
; 1992 Sep; 30(9): 850-2
Article
em En
| IMSEAR
| ID: sea-62857
ABSTRACT
Phosphamidon intoxication (2 mg/kg body wt./day for 7 days) inhibited SOD activity, but enhanced the lipid peroxidation in various CNS regions. Administration of cithiolone (8 mg/kg body wt./day, ip for 7 days), however, elevated SOD activity and depleted lipid peroxidation. Interestingly, no significant change was observed either in SOD activity or in lipid peroxidation following simultaneous administration of phosphamidon and cithiolone.
Texto completo:
1
Índice:
IMSEAR
Assunto principal:
Fosfamidona
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Ratos
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Superóxido Dismutase
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Tiofenos
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Masculino
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Peroxidação de Lipídeos
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Sistema Nervoso Central
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Animais
Idioma:
En
Revista:
Indian J Exp Biol
Ano de publicação:
1992
Tipo de documento:
Article