Helicobacter pylori infection at a university hospital in Saudi Arabia: prevalence, comparison of diagnostic modalities and endoscopic findings.
Indian J Pathol Microbiol
; 2005 Apr; 48(2): 181-5
Article
em En
| IMSEAR
| ID: sea-74619
ABSTRACT
The presence of Helicobacter pylori (H. pylori) was examined in 491 sequential patients, complaining mainly of epigastric pain, by three biopsy-based methods (rapid urease, histology, and culture), and by a serological test, enzyme immunosorbent assay, (ELISA). H. pylori was detected in 341 (70%) of 491 patients examined by histology, 287 (59%) by rapid urease test, whereas 385 (78%) were seropositive for H. pylori immunoglobulins by ELISA. None of the test methods used was independently sufficient to make an etiologic diagnosis of H. pylori infection. The endoscopic findings revealed that 315 (69%) of 456 patients with non-ulcer dyspepsia, 17 (74%) of 23 patients with duodenal ulcer, 7 (78%) of 9 patients with gastric ulcer, and 2 (67%) of 3 patients with gastric cancer were H. pylori positive. No statistically significant correlation was found between the endoscopic and the histopathological findings. A significant correlation was found between H. pylori infection and the histopathological gradings of gastritis (P < 0.001).
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Índice:
IMSEAR
Assunto principal:
Arábia Saudita
/
Urease
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Idoso de 80 Anos ou mais
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Idoso
/
Feminino
/
Humanos
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Masculino
/
Imunoglobulinas
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Criança
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Helicobacter pylori
Tipo de estudo:
Diagnostic_studies
/
Prevalence_studies
Limite:
Aged80
País/Região como assunto:
Asia
Idioma:
En
Revista:
Indian J Pathol Microbiol
Ano de publicação:
2005
Tipo de documento:
Article