Biochemical abnormalities in neonatal seizures.
Indian Pediatr
; 1995 Apr; 32(4): 424-8
Article
em En
| IMSEAR
| ID: sea-8123
ABSTRACT
Early diagnosis and appropriate treatment of biochemical abnormalities accompanying neonatal seizures is important for effective seizure control and to avoid further brain damage. The present study was carried out on 35 neonates to determine the frequency of various biochemical abnormalities in neonatal seizures. Diagnostic evaluation included estimation of levels of serum calcium, phosphorus, magnesium, sodium, potassium, zinc, and blood glucose. Two-thirds of the neonates with seizures had biochemical disturbances in their sera. A variety of abnormalities occurred in asphyxiated infants, including hyponatremia, hypoglycemia, hypocalcemia, and hypomagnesemia. Primary metabolic disorders accounted for one-forth of the cases of neonatal seizures, the most common being hypoglycemia, hypoglycemia/hypocalcemia, and hypocalcemia/hyperphosphatemia. Inappropriate intrauterine growth, inadequate feeding, and feeding with cow's milk were the main risk factors for primary metabolic seizures. Hyponatremia was a frequent finding in seizures resulting from brain damage like birth asphyxia, meningitis, and intracranial hemorrhage. No infant had hypernatremia, hyperkalemia, hypokalemia, or low serum zinc.
Texto completo:
1
Índice:
IMSEAR
Assunto principal:
Prognóstico
/
Convulsões
/
Fenômenos Bioquímicos
/
Bioquímica
/
Humanos
/
Recém-Nascido
/
Índia
/
Doenças do Recém-Nascido
/
Doenças Metabólicas
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
País/Região como assunto:
Asia
Idioma:
En
Revista:
Indian Pediatr
Ano de publicação:
1995
Tipo de documento:
Article