Advances in enzymatic production of L-homophenylalanine / 生物工程学报
Chinese Journal of Biotechnology
; (12): 3111-3124, 2023.
Article
em Zh
| WPRIM
| ID: wpr-1007948
Biblioteca responsável:
WPRO
ABSTRACT
L-homophenylalanine (L-HPA) is an important non-natural amino acid that has been used as a key intermediate for the synthesis of Puli drugs for the treatment of hypertension. At present, L-HPA is synthesized using chemical methods, which has the disadvantages of expensive raw materials, tedious steps and serious pollution. Therefore, researchers have conducted in-depth research on the enzymatic production of L-HPA. This review summarizes the research progress on the enzymatic synthesis of L-HPA, including the dehydrogenase process, the transaminase process, the hydantoinase process, and the decarboxylase process, with the hope to facilitate the industrial production of L-HPA.
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Texto completo:
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Índice:
WPRIM
Assunto principal:
Biossíntese de Proteínas
/
Poluição Ambiental
/
Aminoácidos
/
Indústrias
Idioma:
Zh
Revista:
Chinese Journal of Biotechnology
Ano de publicação:
2023
Tipo de documento:
Article