Research progress of biomarkers of hepatitis B virus and clinical significance / 生物医学工程学杂志
Journal of Biomedical Engineering
; (6): 1242-1248, 2023.
Article
em Zh
| WPRIM
| ID: wpr-1008956
Biblioteca responsável:
WPRO
ABSTRACT
The infection of Hepatitis B virus (HBV) can result in severe consequences, including chronic hepatitis, liver fibrosis, cirrhosis, and even liver cancer. Effective antiviral treatment has the potential to slow down the progression of the disease. HBV serum biomarkers play a crucial role in the dynamic management of chronic hepatitis B (CHB) patients. However, the conventional hepatitis B virus markers, such as hepatitis B serologic testing and HBV DNA, are insufficient to meet the clinical requirements. This review provided a comprehensive overview of the current research on the quantification of HBsAg and anti-HBc, HBV RNA and HBV core-associated antigen, which summarized the crucial role these markers play in the administration of antiviral medications, predicting the efficacy of treatment and anticipating the likelihood of virologic rebound following drug cessation, as well as assessing disease progression in CHB patients.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Antivirais
/
DNA Viral
/
Biomarcadores
/
Vírus da Hepatite B
/
Hepatite B Crônica
/
Relevância Clínica
/
Hepatite B
/
Antígenos do Núcleo do Vírus da Hepatite B
/
Antígenos E da Hepatite B
/
Antígenos de Superfície da Hepatite B
Limite:
Humans
Idioma:
Zh
Revista:
Journal of Biomedical Engineering
Ano de publicação:
2023
Tipo de documento:
Article