Mechanism of PSMD10 in homocysteine activating hepatocyte autophagy and promoting liver injury

Xin-Yan WU; Qing-Qing WANG; Long XU; Hui ZHANG; Wei GUO; An-Ning YANG; Yi-Deng JIANG; Xin-Yan WU; Qing-Qing WANG; Long XU; Hui ZHANG; Wei GUO; An-Ning YANG; Yi-Deng JIANG; Xin-Yan WU; Qing-Qing WANG; Long XU; Hui ZHANG; Wei GUO; An-Ning YANG; Yi-Deng JIANG; Yun JIAO; Yin-Ju HAO

Mechanism of PSMD10 in homocysteine activating hepatocyte autophagy and promoting liver injury / 中国药理学通报

Xin-Yan WU; Qing-Qing WANG; Long XU; Hui ZHANG; Wei GUO; An-Ning YANG; Yi-Deng JIANG; Xin-Yan WU; Qing-Qing WANG; Long XU; Hui ZHANG; Wei GUO; An-Ning YANG; Yi-Deng JIANG; Xin-Yan WU; Qing-Qing WANG; Long XU; Hui ZHANG; Wei GUO; An-Ning YANG; Yi-Deng JIANG; Yun JIAO; Yin-Ju HAO.

Chinese Pharmacological Bulletin ; (12): 535-541, 2021.

Article em Zh | WPRIM | ID: wpr-1014395

Biblioteca responsável: WPRO

ABSTRACT

ABSTRACT

Aim To discuss the mechanism of proteasome 26S subunit non-ATPase 10(PSMD10) activating hepatocyte autophagy and promoting liver injury by in homocysteine. Methods Wild mice and cystathionine β-synthase (CBS) gene knockout mice were used and divided into normal (cbs

Palavras-chave

ALT; AST; autophagy; Hcy; hepatocyte; liver injury; PSMD10

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Texto completo: 1 Índice: WPRIM Idioma: Zh Revista: Chinese Pharmacological Bulletin Ano de publicação: 2021 Tipo de documento: Article

Texto completo

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Texto completo: 1 Índice: WPRIM Idioma: Zh Revista: Chinese Pharmacological Bulletin Ano de publicação: 2021 Tipo de documento: Article