Introduction and application of non-parametric regression method in medical research / 复旦学报(医学版)
Fudan University Journal of Medical Sciences
; (6): 280-284, 2024.
Article
em Zh
| WPRIM
| ID: wpr-1019615
Biblioteca responsável:
WPRO
ABSTRACT
This article introduced the basic theory of non-parametric regression and its application in medical and public health research for methodological reference.We conducted Cox proportional hazard models with restricted cubic splines using chronic disease management data from a Center for Disease Control and Prevention.We aimed to explore the separate and combined effects of mean fasting blood glucose level and glucose variability on all-cause mortality among individuals with type 2 diabetes.A non-linear association was observed between glucose variability and the risk of all-cause mortality.The association between glucose variability and all-cause mortality was stronger at higher mean fasting blood glucose levels compared to lower levels.The non-parametric regression methods comprehensively explored dose-response relationships between continuous exposure and outcome,revealing the combined effects of continuous exposures,which provided recommendations for targeted interventions.The method showed promising application value in medical and public health research.
Texto completo:
1
Índice:
WPRIM
Idioma:
Zh
Revista:
Fudan University Journal of Medical Sciences
Ano de publicação:
2024
Tipo de documento:
Article