Research Progress on Chemical Constituents and Pharmacological Effects of Angelica acutiloba(Sieb.et Zucc.)Kitagawa / 世界科学技术-中医药现代化

ABSTRACT

Angelica acutiloba(Sieb.et Zucc.)Kitagawa(AAK)is applied at Japan,Korea and Chaoxian nationality in China,which conceals exploiting potential and application value.The information of A.acutiloba was summarized base on CNKI and Pubmed databases,combining with Herb,Pubchem,Chemical book databases.Nowadays the compounds of AAK consist of volatile oil,coumarins,flavonoids,polysaccharide and so on.Due to the different planting methods and production areas,the content of compounds varies from region to region.Various of AAK compounds exert pharmacological activity through multiple pathways.It's aqueous extract,alcohol extract and partial monomer play an important role in regulating multiple systems such as the circulatory system,nervous system,and immune system.Those ingredients improve the pharmacological activities of hematopoietic and cardiovascular system,protect liver,combat inflammation,resist bacteria,improve learning and memory function,retard photoaging and resist tumor.In this paper,the progress of chemical constituents and pharmacology activity of AAK were sorted out from recent two decades,so as to offer assistance for therapeutic material basis,development of medicinal resource and clinical utilization.