Possible mechanisms of type 2 diabetes mellitus improvement via exercise-induced changes in gut microbiota composition and metabolites / 中国免疫学杂志

ABSTRACT

Type 2 diabetes mellitus(T2DM)is a common chronic metabolic disease,while there is no consistent conclusion on the pathogenesis of T2DM.With the innovation of microecological research technology,intestinal dysbiosis is considered to be one of the causes of T2DM.Exercise is one of the effective means of diabetes management,while mechanism of regulating glucose metabo-lism still has many problems to be solved.In recent years,people have found that exercise can improve the intestinal environment and intestinal flora.This article will review the research on the influence and mechanism of exercise on T2DM based on intestinal flora,aiming to provide new ideas for exploring how exercise can improve T2DM in the future.