Progress in the study of thymosin α1 in infectious diseases / 中国医师杂志

ABSTRACT

Infection is a common disease that can be life-threatening. It can lead to shock, multiple organ failure, and even death in severe cases. Immune disorders can make patients more prone to infection and adverse outcomes related to it. Thymosin α1 (Tα1) is a 28-amino acid synthetic peptide related to thymopentin. Numerous in vivo and in vitro studies have demonstrated its anti-infectious effects by immune regulation. In this article, we will review the nature and characteristics of Tα1, its mechanism of action, and its application in viruses, fungi, and bacterial infections. We will also summarize and evaluate its research progress in various infectious diseases.