TNF-alpha Inhibitor Treatment in an Ankylosing Spondylitis Patient with Secondary Amyloidosis that Manifest with Diarrhea: A Case Report / 대한내과학회지
Korean Journal of Medicine
; : 259-263, 2015.
Article
em Ko
| WPRIM
| ID: wpr-102971
Biblioteca responsável:
WPRO
ABSTRACT
Secondary amyloidosis (Amyloid A amyloidosis) occurs when serum amyloid S accumulates in various tissues and organs. It often accompanies chronic inflammatory disease, especially rheumatoid arthritis, as well as ankylosing spondylitis (AS) and Crohn's disease. Although amyloid deposits were reported in 7% of the abdominal fatty tissue samples from AS patients, most of the patients had no symptoms. In a large study, 1.1% of 730 patients with AS were diagnosed with amyloidosis. Most of them showed renal involvement, while none had gastrointestinal symptoms. In South Korea, only a few cases of gastrointestinal involvement of secondary amyloidosis have been reported in AS patients, and there is no report on the effect of a tumor necrosis factor (TNF)-alpha inhibitor. We report a case of secondary amyloidosis in an AS patient who improved with the TNF-alpha inhibitor etanercept.
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Texto completo:
1
Índice:
WPRIM
Assunto principal:
Artrite Reumatoide
/
Espondilite Anquilosante
/
Doença de Crohn
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Tecido Adiposo
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Fator de Necrose Tumoral alfa
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Placa Amiloide
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Diarreia
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Etanercepte
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Amiloide
/
Amiloidose
Limite:
Humans
País/Região como assunto:
Asia
Idioma:
Ko
Revista:
Korean Journal of Medicine
Ano de publicação:
2015
Tipo de documento:
Article