Aspergillus fumigatus Scleritis Associated with Monoclonal Gammopathy of Undetermined Significance
Korean Journal of Ophthalmology
; : 175-178, 2010.
Article
em En
| WPRIM
| ID: wpr-103546
Biblioteca responsável:
WPRO
ABSTRACT
A 68-year-old woman presented with pain in her left eye. Necrosis with calcium plaques was observed on the medial part of the sclera. Aspergillus fumigatus was isolated from the culture of the necrotic area. On systemic work-up including serum and urine electrophoresis studies, the serum monoclonal protein of immunoglobulin G was detected. The patient was diagnosed with monoclonal gammopathy of undetermined significance and fungal scleritis. Despite intensive treatment with topical and oral antifungal agents, scleral inflammation and ulceration progressed, and scleral perforation and endophthalmitis developed. Debridement, antifungal irrigation, and tectonic scleral grafting were performed. The patient underwent a combined pars plana vitrectomy with an intravitreal injection of an antifungal agent. However, scleral and intraocular inflammation progressed, and the eye was enucleated. Aspergillus fumigatus was isolated from the cultures of the eviscerated materials. Giemsa staining of the excised sclera showed numerous fungal hyphae.
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Texto completo:
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Índice:
WPRIM
Assunto principal:
Paraproteinemias
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Aspergilose
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Aspergillus fumigatus
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Esclera
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Vitrectomia
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Enucleação Ocular
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Esclerite
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Anfotericina B
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Progressão da Doença
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Injeções Intraoculares
Limite:
Aged
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Female
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Humans
Idioma:
En
Revista:
Korean Journal of Ophthalmology
Ano de publicação:
2010
Tipo de documento:
Article