Clinical analysis of Trousseau syndrome with acute cerebral infarction as the first manifestation of 12 cases / 中风与神经疾病杂志

ABSTRACT

@#Objective　To improve the skills of diagnosis and treatment of Trousseau syndrome in order to reduce misdiagnosis and mistreatment.Methods　Twelve cases admitted in our hospital and subsequently proved Trousseau syndrome were retrospectively analyzed,including their clinical characteristics,radiography results,and treatment effect.Results　Twelve cases began as acute cerebral infarction,associated with increased D-dimer in ten cases and multiple acute infarction involving multiple arterial innervation region in MR of all cases.Among twelve cases,seven cases of lung cancer,one case of pancreatic cancer,two cases of breast cancer and two cases of ovarian cancer were finally diagnosed.Then,six patients were treated with anticoagulant therapy and six abandoned.Conclusion　If the lesions’ distribution of acute cerebral infarction doesn’t conform to the conventional and single arterial innervation region in aged patients,doctors should search causes actively,especially should be vigilant about Trousseau syndrome,in order to treat correctly and prevent recurrent episodes that aggravate the disease.