Guidelines for Manufacturing and Application of Organoids: Skin
International Journal of Stem Cells
; : 182-193, 2024.
Article
em En
| WPRIM
| ID: wpr-1043060
Biblioteca responsável:
WPRO
ABSTRACT
To address the limitations of animal testing, scientific research is increasingly focused on developing alternative testing methods. These alternative tests utilize cells or tissues derived from animals or humans for in vitro testing, as well as artificial tissues and organoids. In western countries, animal testing for cosmetics has been banned, leading to the adoption of artificial skin for toxicity evaluation, such as skin corrosion and irritation assessments. Standard guidelines for skin organoid technology becomes necessary to ensure consistent data and evaluation in replacing animal testing with in vitro methods. These guidelines encompass aspects such as cell sourcing, culture techniques, quality requirements and assessment, storage and preservation, and organoid-based assays.
Texto completo:
1
Índice:
WPRIM
Idioma:
En
Revista:
International Journal of Stem Cells
Ano de publicação:
2024
Tipo de documento:
Article