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Primary Bilateral Adrenal Non-Hodgkin's Lymphoma Presented with Adrenal Insufficiency: A Case Report
Article em En | WPRIM | ID: wpr-115541
Biblioteca responsável: WPRO
ABSTRACT
Primary adrenal lymphoma is a very rare disease and it is known to have a poor prognosis. We report here on a case of primary adrenal insufficiency that was secondary to primary bilateral adrenal lymphoma. A 54-year old man was hospitalized because of easy fatigability, weight loss and consistent malaise for 6 months. The physical examination revealed hyperpigmentation on the anterior chest and hypotension. According these findings and symptoms, we did a rapid ACTH stimulation test with a clinical suspicion of adrenal insufficiency. He showed an inadequate adrenal response and so he was diagnosed with adrenal insufficiency. The abdominal CT images showed bilateral huge adrenal masses and increased uptake of the adrenal glands on PET. The pathologic diagnosis by ultrasound-guided gun biopsy of the right adrenal gland was diffuse large B cell lymphoma. The patient was administered combination chemotherapy with the R-CHOP regimen, and after 8-cycles of chemotherapy, he achieved complete remission of tumor according to the image studies and he recovered his adrenal function. Primary adrenal lymphoma, although a rare disease, should be considered in patients with bilateral enlargement of the adrenal glands and when the adrenal glands show increased uptake on a PET scan, and especially there is adrenal insufficiency.
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Texto completo: 1 Índice: WPRIM Assunto principal: Exame Físico / Prognóstico / Tórax / Biópsia / Linfoma não Hodgkin / Doença de Addison / Redução de Peso / Linfoma de Células B / Hiperpigmentação / Insuficiência Adrenal Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Endocrinology and Metabolism Ano de publicação: 2011 Tipo de documento: Article
Texto completo: 1 Índice: WPRIM Assunto principal: Exame Físico / Prognóstico / Tórax / Biópsia / Linfoma não Hodgkin / Doença de Addison / Redução de Peso / Linfoma de Células B / Hiperpigmentação / Insuficiência Adrenal Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Endocrinology and Metabolism Ano de publicação: 2011 Tipo de documento: Article