A Case of Aconite Poisoning Successfully Recovered after Intravenous Fat Emulsion Therapy
Journal of The Korean Society of Clinical Toxicology
; : 60-65, 2016.
Article
em Ko
| WPRIM
| ID: wpr-136326
Biblioteca responsável:
WPRO
ABSTRACT
Aconitum is a genus of various species of flowering plants that belongs to the Family Ranunculaceae. Most Aconitum sp. have extremely toxic alkaloid substances such as aconitine, mesaconitine and hypaconitine. Among these substances, aconitine can cause fatal cardiotoxicity by activating sodium channels followed by calcium channels in myocardial cells. Even though there have been various therapeutic plans suggested comprising antidotes based on diverse case reports and studies, there is no confirmatory treatment protocol for aconite poisoning. Here, we report an aconite poisoning patient who had refractory ventricular tachyarrhythmia that did not respond to intravenous amiodarone therapies even though they were sustained for over 2 hours, but showed successful recovery following intravenous fat emulsions (IFE) therapy.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Intoxicação
/
Taquicardia
/
Aconitina
/
Canais de Cálcio
/
Canais de Sódio
/
Protocolos Clínicos
/
Ranunculaceae
/
Aconitum
/
Flores
/
Emulsões Gordurosas Intravenosas
Tipo de estudo:
Guideline
Limite:
Humans
Idioma:
Ko
Revista:
Journal of The Korean Society of Clinical Toxicology
Ano de publicação:
2016
Tipo de documento:
Article