Early Sodium and Fluid Intake and Severe Intraventricular Hemorrhage in Extremely Low Birth Weight Infants
Journal of Korean Medical Science
; : 283-289, 2015.
Article
em En
| WPRIM
| ID: wpr-138285
Biblioteca responsável:
WPRO
ABSTRACT
Hypernatremic dehydration is an important cause of intracranial hemorrhage. A possible association of intraventricular hemorrhage (IVH) with hypernatremia and/or high sodium intake has been suggested in preterm infants. To investigate the associations of early fluid and sodium intake or serum sodium concentrations with severe intraventricular hemorrhage (IVH) in extremely low birth weight (ELBW) infants, we reviewed the medical records of 169 inborn ELBW infants. Daily fluid and sodium intake, urine output, weight loss and serum sodium concentration during the first 4 days of life were obtained. Patients were divided into the severe IVH (grade 3/4) and the control (no or grade 1/2 IVH) group. The maximum serum sodium concentration and the incidence of hypernatremia did not differ between the two groups. Related to the fluid balance and sodium intake, the risk for severe IVH was strongly associated with total fluid and sodium intake during the initial four days of life. With respect to the fluids other than transfusion, severe IVH can be discriminated only by sodium intake but not by fluid intake. Large randomized controlled trials are required to clarify the causal relationship between the early sodium intake and severe IVH in ELBW infants.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Sódio
/
Peso ao Nascer
/
Recém-Nascido Prematuro
/
Sódio na Dieta
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Mortalidade Infantil
/
Estudos Retrospectivos
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Desidratação
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Ingestão de Líquidos
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Recém-Nascido de Peso Extremamente Baixo ao Nascer
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Ventrículos do Coração
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Humans
/
Infant
/
Newborn
Idioma:
En
Revista:
Journal of Korean Medical Science
Ano de publicação:
2015
Tipo de documento:
Article