Usefulness of the Controlled Attenuation Parameter for Detecting Liver Steatosis in Health Checkup Examinees
Gut and Liver
; : 405-410, 2015.
Article
em En
| WPRIM
| ID: wpr-142462
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND/AIMS:
The controlled attenuation parameter (CAP) implemented in FibroScan(R) is reported to be a non-invasive means of detecting steatosis (>10% steatosis). We aimed to evaluate the usefulness of CAP in detecting steatosis among health checkup examinees and to assess its correlation with ultrasonography (US).METHODS:
Consecutive CAP results were retrospectively collected. A total of 280 subjects were included.RESULTS:
Fatty liver was detected in 119 subjects (42.5%) by US, whereas it was detected in 160 subjects (57.1%) by the CAP. The numbers of subjects with S0S1S2S3 steatosis according to the CAP value were 120595843, respectively. The mean CAP values were 203.34+/-28.39 dB/m for S0, 248.83+/-6.14 dB/m for S1, 274.33+/-8.53 dB/m for S2, and 322.35+/-22.20 dB/m for S3. CAP values were correlated with body weight (r=0.404, p<0.001), body mass index (r=0.445, p<0.001), and the fatty liver grade by US (r=0.472, p<0.001). Among the 161 subjects with normal US findings, steatosis was detected in 65 subjects (40.4%) using the CAP.CONCLUSIONS:
The CAP seems to be useful for detecting very low-grade hepatic steatosis in health checkup examinees. Its role in predicting subjects with a risk of metabolic derangement needs to be evaluated.Palavras-chave
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Índice:
WPRIM
Assunto principal:
Exame Físico
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Índice de Gravidade de Doença
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Peso Corporal
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Índice de Massa Corporal
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Valor Preditivo dos Testes
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Estudos Retrospectivos
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Curva ROC
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Técnicas de Imagem por Elasticidade
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Fígado Gorduroso
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Fígado
Tipo de estudo:
Diagnostic_studies
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Observational_studies
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Prognostic_studies
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Screening_studies
Limite:
Adult
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Female
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Humans
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Male
Idioma:
En
Revista:
Gut and Liver
Ano de publicação:
2015
Tipo de documento:
Article