A Small Pancreatic Neuroendocrine Tumor with Marked Pancreatic Duct Dilatation and Parenchymal Atrophy / 대한내과학회지
Korean Journal of Medicine
; : 598-602, 2014.
Article
em Ko
| WPRIM
| ID: wpr-151957
Biblioteca responsável:
WPRO
ABSTRACT
Pancreatic ductal adenocarcinomas often cause marked pancreatic duct dilatation and associated parenchymal atrophy. We present the case of a small pancreatic neuroendocrine tumor with upstream pancreatic duct dilatation and severe parenchymal atrophy. A small enhancing tumor was observed at the head of the pancreas on computed tomography (CT). Endoscopic ultrasonography-guided fine-needle aspiration was negative for malignancy. We performed a pylorus-preserving pancreatoduodenectomy since we could not exclude the presence of pancreatic ductal adenocarcinoma. The pathological and immunohistochemical examination revealed a serotonin-positive neuroendocrine tumor, measured 1.0 x 0.5 cm. The pathological specimen was remarkable for the marked stromal fibrosis in the area of the tumor, which resulted in narrowing of the main pancreatic duct. Here, we report a rare small pancreatic neuroendocrine tumor, the CT image of which resembled that of pancreatic ductal adenocarcinoma, in which the expression of serotonin and associated fibrosis might be a possible mechanism for the marked main pancreatic duct dilatation.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Pâncreas
/
Ductos Pancreáticos
/
Atrofia
/
Fibrose
/
Adenocarcinoma
/
Serotonina
/
Pancreaticoduodenectomia
/
Tumores Neuroendócrinos
/
Biópsia por Agulha Fina
/
Dilatação
Idioma:
Ko
Revista:
Korean Journal of Medicine
Ano de publicação:
2014
Tipo de documento:
Article