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Obesity and Hyperglycemia in Korean Men with Klinefelter Syndrome: The Korean Endocrine Society Registry
Article em En | WPRIM | ID: wpr-154211
Biblioteca responsável: WPRO
ABSTRACT
BACKGROUND: The aim of this study was to investigate the prevalence of obesity in Korean men with Klinefelter syndrome (KS) and the associated risk factors for obesity and hyperglycemia. METHODS: Data were collected retrospectively from medical records from 11 university hospitals in Korea between 1994 and 2014. Subjects aged ≥18 years with newly diagnosed KS were enrolled. The following parameters were recorded at baseline before treatment: chief complaint, height, weight, fasting glucose level, lipid panel, blood pressure, testosterone, luteinizing hormone, follicle-stimulating hormone, karyotyping patterns, and history of hypertension, diabetes, and dyslipidemia. RESULTS: Data were analyzed from 376 of 544 initially enrolled patients. The rate of the 47 XXY chromosomal pattern was 94.1%. The prevalence of obesity (body mass index ≥25 kg/m²) in Korean men with KS was 42.6%. The testosterone level was an independent risk factor for obesity and hyperglycemia. CONCLUSION: Obesity is common in Korean men with KS. Hypogonadism in patients with KS was associated with obesity and hyperglycemia.
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Texto completo: 1 Índice: WPRIM Assunto principal: Testosterona / Pressão Sanguínea / Hormônio Luteinizante / Prontuários Médicos / Prevalência / Estudos Retrospectivos / Fatores de Risco / Jejum / Dislipidemias / Hormônio Foliculoestimulante Tipo de estudo: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Humans / Male País/Região como assunto: Asia Idioma: En Revista: Endocrinology and Metabolism Ano de publicação: 2016 Tipo de documento: Article
Texto completo: 1 Índice: WPRIM Assunto principal: Testosterona / Pressão Sanguínea / Hormônio Luteinizante / Prontuários Médicos / Prevalência / Estudos Retrospectivos / Fatores de Risco / Jejum / Dislipidemias / Hormônio Foliculoestimulante Tipo de estudo: Etiology_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Humans / Male País/Região como assunto: Asia Idioma: En Revista: Endocrinology and Metabolism Ano de publicação: 2016 Tipo de documento: Article