A Prediction Rule to Identify Severe Cases among Adult Patients Hospitalized with Pandemic Influenza A (H1N1) 2009
Journal of Korean Medical Science
; : 499-506, 2011.
Article
em En
| WPRIM
| ID: wpr-173914
Biblioteca responsável:
WPRO
ABSTRACT
The purpose of this study was to establish a prediction rule for severe illness in adult patients hospitalized with pandemic influenza A (H1N1) 2009. At the time of initial presentation, the baseline characteristics of those with severe illness (i.e., admission to intensive care unit, mechanical ventilation, or death) were compared to those of patients with non-severe illnesses. A total of 709 adults hospitalized with pandemic influenza A (H1N1) 2009 were included: 75 severe and 634 non-severe cases. The multivariate analysis demonstrated that altered mental status, hypoxia (PaO2/FiO2 or = 65 yr) were independent risk factors for severe cases (all P or = 2 risk factors had a higher sensitivity, specificity, positive predictive value and negative predictive value than an APACHE II score of > or = 13. As a prediction rule, the presence of > or = 2 these risk factors is a powerful and easy-to-use predictor of the severity in adult patients hospitalized with pandemic influenza A (H1N1) 2009.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Antivirais
/
Respiração Artificial
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Índice de Gravidade de Doença
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Valor Preditivo dos Testes
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Fatores de Risco
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Curva ROC
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APACHE
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Influenza Humana
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Vírus da Influenza A Subtipo H1N1
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Pandemias
Tipo de estudo:
Etiology_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Adult
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Aged
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Female
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Humans
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Male
Idioma:
En
Revista:
Journal of Korean Medical Science
Ano de publicação:
2011
Tipo de documento:
Article